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US · SION

Sionna Therapeutics, Inc.

Programmatic access: InvestorsCraft Valuation API · catalog

Sector
Healthcare · Biotechnology
Headquarters
Waltham, MA 02451

Price · as of 2026-09-04

$7.18

Market cap 2.3B

Price history

Weekly OHLC price history for SION, USD per share
WeekOpenHighLowCloseVolume
Feb 3, 2025 – Feb 7, 2025$25.00$25.19$21.10$25.00
Feb 10, 2025 – Feb 14, 2025$23.71$24.90$19.26$20.030
Feb 17, 2025 – Feb 21, 2025$20.75$20.96$19.50$19.760
Feb 24, 2025 – Feb 28, 2025$19.66$20.36$13.21$13.770
Mar 3, 2025 – Mar 7, 2025$13.56$17.20$13.37$16.270
Mar 10, 2025 – Mar 14, 2025$16.60$17.81$14.23$14.980
Mar 17, 2025 – Mar 21, 2025$14.86$16.70$11.95$13.690
Mar 24, 2025 – Mar 28, 2025$13.83$14.09$11.25$11.560
Mar 31, 2025 – Apr 4, 2025$10.90$13.13$9.37$9.970
Apr 7, 2025 – Apr 11, 2025$9.24$10.72$7.26$7.870
Apr 14, 2025 – Apr 17, 2025$7.98$11.51$7.76$11.070
Apr 21, 2025 – Apr 25, 2025$10.57$13.42$10.07$12.140
Apr 28, 2025 – May 2, 2025$11.85$14.52$10.97$13.580
May 5, 2025 – May 9, 2025$13.15$13.53$12.07$12.320
May 12, 2025 – May 16, 2025$12.45$14.50$11.77$13.430
May 19, 2025 – May 23, 2025$13.29$14.60$12.42$12.720
May 26, 2025 – May 30, 2025$13.29$14.66$12.53$13.690
Jun 2, 2025 – Jun 6, 2025$13.94$17.40$13.33$17.220
Jun 9, 2025 – Jun 13, 2025$17.49$18.85$15.99$16.380
Jun 16, 2025 – Jun 20, 2025$16.02$16.02$13.51$14.490
Jun 23, 2025 – Jun 27, 2025$14.73$16.28$13.81$15.840
Jun 30, 2025 – Jul 3, 2025$15.65$21.94$15.10$21.190
Jul 7, 2025 – Jul 11, 2025$20.84$21.87$19.95$20.430
Jul 14, 2025 – Jul 18, 2025$20.39$20.99$16.59$16.740
Jul 21, 2025 – Jul 25, 2025$16.46$20.06$16.46$19.100
Jul 28, 2025 – Aug 1, 2025$18.87$20.55$16.38$16.920
Aug 4, 2025 – Aug 8, 2025$17.02$18.22$16.48$17.670
Aug 11, 2025 – Aug 15, 2025$18.61$21.70$17.11$20.820
Aug 18, 2025 – Aug 22, 2025$20.94$25.00$20.50$24.390
Aug 25, 2025 – Aug 29, 2025$24.30$26.50$23.67$24.620
Sep 1, 2025 – Sep 5, 2025$24.48$26.48$21.70$24.000
Sep 8, 2025 – Sep 12, 2025$24.99$26.47$20.60$22.830
Sep 15, 2025 – Sep 19, 2025$22.85$24.77$21.74$23.140
Sep 22, 2025 – Sep 26, 2025$23.14$29.02$22.79$28.940
Sep 29, 2025 – Oct 3, 2025$28.94$30.61$26.76$30.010
Oct 6, 2025 – Oct 10, 2025$29.95$30.14$24.65$29.420
Oct 13, 2025 – Oct 17, 2025$29.68$34.00$28.89$31.930
Oct 20, 2025 – Oct 24, 2025$32.34$43.20$31.06$39.210
Oct 27, 2025 – Oct 31, 2025$39.34$40.08$36.06$38.210
Nov 3, 2025 – Nov 7, 2025$37.16$39.49$32.40$34.710
Nov 10, 2025 – Nov 14, 2025$35.12$37.98$34.34$37.000
Nov 17, 2025 – Nov 21, 2025$37.70$43.93$36.81$43.660
Nov 24, 2025 – Nov 28, 2025$44.00$45.00$41.87$43.570
Dec 1, 2025 – Dec 5, 2025$40.76$43.90$35.42$40.290
Dec 8, 2025 – Dec 12, 2025$40.13$43.20$39.91$42.770
Dec 15, 2025 – Dec 19, 2025$43.41$45.00$41.18$42.370
Dec 22, 2025 – Dec 26, 2025$42.07$44.70$40.48$43.700
Dec 29, 2025 – Jan 2, 2026$43.70$45.00$38.93$39.210
Jan 5, 2026 – Jan 9, 2026$39.00$43.30$35.95$39.250
Jan 12, 2026 – Jan 16, 2026$39.03$41.73$34.63$39.110
Jan 19, 2026 – Jan 23, 2026$38.32$43.14$37.70$42.380
Jan 26, 2026 – Jan 30, 2026$40.91$44.19$40.31$42.260
Feb 2, 2026 – Feb 6, 2026$42.06$44.99$32.46$36.110
Feb 9, 2026 – Feb 13, 2026$35.97$39.87$35.02$37.520
Feb 16, 2026 – Feb 20, 2026$37.53$38.91$35.46$35.490
Feb 23, 2026 – Feb 27, 2026$34.99$39.32$34.72$36.540
Mar 2, 2026 – Mar 6, 2026$32.89$36.23$32.57$35.930
Mar 9, 2026 – Mar 13, 2026$35.58$39.17$34.63$37.320
Mar 16, 2026 – Mar 20, 2026$37.65$39.03$33.20$36.390
Mar 23, 2026 – Mar 27, 2026$36.99$38.71$33.65$36.160
Mar 30, 2026 – Apr 2, 2026$36.18$42.62$35.36$40.490
Apr 6, 2026 – Apr 10, 2026$40.09$40.42$35.39$37.890
Apr 13, 2026 – Apr 17, 2026$37.95$46.46$36.91$43.540
Apr 20, 2026 – Apr 24, 2026$43.54$44.71$35.10$38.110
Apr 27, 2026 – May 1, 2026$38.02$42.21$36.50$39.150
May 4, 2026 – May 8, 2026$38.64$45.80$38.64$44.230
May 11, 2026 – May 15, 2026$44.68$48.45$40.07$40.220
May 18, 2026 – May 22, 2026$41.46$43.42$36.90$41.130
May 25, 2026 – May 29, 2026$41.68$44.61$40.53$42.820
Jun 1, 2026 – Jun 5, 2026$41.87$42.07$35.25$35.370
Jun 8, 2026 – Jun 12, 2026$35.29$37.17$32.26$35.920
Jun 15, 2026 – Jun 18, 2026$36.54$38.56$33.99$37.300
Jun 22, 2026 – Jun 26, 2026$37.89$44.30$37.28$42.180
Jun 29, 2026 – Jul 2, 2026$42.29$45.00$40.92$43.990
Jul 6, 2026 – Jul 10, 2026$44.01$46.98$42.24$45.290
Jul 13, 2026 – Jul 17, 2026$45.40$51.00$41.69$49.410
Jul 20, 2026 – Jul 24, 2026$50.20$51.57$43.41$45.700
Jul 27, 2026 – Jul 31, 2026$46.03$47.89$44.11$47.130
Aug 3, 2026 – Aug 7, 2026$46.86$54.97$45.57$51.040
Aug 10, 2026 – Aug 14, 2026$4.85$6.75$4.01$6.460
Aug 17, 2026 – Aug 21, 2026$6.47$6.80$5.27$5.290
Aug 24, 2026 – Aug 28, 2026$5.29$6.30$5.21$5.870
Aug 31, 2026 – Sep 4, 2026$5.87$7.56$5.75$7.180

Valuation

MetricValueUpside
IC Value
P/E-19.81
P/B4.86
P/S
EV/EBITDA-16.94
PEG-57.79
P/TBV4.86

Valuation history

Annual price overlaid with each model's fair value. Y-axis is log scale.

Annual price and model valuations for SION, USD per share
YearPriceAIICGraham-DoddGraham Formula
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024$16.27
2025$37.32

Historic valuation ratios

Pick a category, then toggle metrics to compare.

USD millions

Line items

    USD millions

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      USD millions

      Line items

        About Sionna Therapeutics, Inc.

        Operating as a biopharmaceutical company, Sionna Therapeutics, Inc. is dedicated to transforming the treatment landscape for individuals with cystic fibrosis. This is achieved by developing innovative medicines designed to restore the normal function of the cystic fibrosis transmembrane conductance regulator.

        CEO
        Michael Cloonan
        Employees
        59
        Beta
        1.32

        Peer comparison

        Same-industry comparables, ranked by market cap.

        Scroll horizontally for additional metrics. Ticker column stays fixed.

        Peer comparison for SION: basic info, valuation models, ratios, profitability, leverage, growth, cash flow, dividends, enterprise value, and Altman Z-score.
        Basic InfoIC ValuationCore ValuationProfitabilityLeverage & LiquidityGrowthCash FlowDividendsEnterprise ValueRisk
        TickerCompany NamePriceMarket CapValueUpsideP/EP/BP/SEV/EBITDAPEGP/TBVGross MarginOperating MarginNet MarginROEROICROADebt/EquityInterest CoverageCurrent RatioQuick RatioNet Debt/EBITDAEPS GrowthSales GrowthFCF GrowthFCF YieldOp Cash Flow RatioCash ROICDividend YieldDividend PayoutShareholder YieldEV/EBITEV/FCFEV/SalesAltman Z-Score
        SIONSionna Therapeutics, Inc.$51.042.3B-19.814.86-16.94-57.794.860.00%0.00%0.00%-105.18%80.21%-29.42%0.0320.6120.140.6734.29%26.24%-4.47%-5.6660.10%0.00%0.00%1.46%-14.21-18.9645.64
        ABCLAbCellera Biologics Inc.$5.921.81B$20.45+245%-7.121.0813.88-4.381.1861.64%-288.98%-194.88%-14.47%-33.39%-10.78%0.1511.3210.69-0.10-10.91%160.56%-6.89%-16.70%-2.04-32.47%0.00%0.00%0.00%-3.00-3.748.681.69
        ARDXArdelyx, Inc.$4.911.21B$15.11+208%-22.628.343.42-45.94-42.728.3489.54%-10.06%-15.12%-36.21%-43.02%-13.14%1.27-1.444.313.80-4.9252.94%22.09%-4.03%-3.16%-0.48-46.17%0.00%0.00%0.00%-32.70-30.473.291.10
        BHVNBiohaven Ltd.$13.632.05B-1.4019.80-1.3731.940.00%0.00%0.00%-310.75%17700.74%-138.54%5.473.182.75-0.08-26.08%4.03%-59.18%-5.2614489.50%0.00%0.00%0.00%-1.34-1.63-9.69
        CLDXCelldex Therapeutics, Inc…$41.062.73B$15.31-63%-7.583.721308.28-5.66-12.813.93100.00%-19160.00%-17253.33%-40.62%-1576.31%-37.63%0.0010.4910.210.1059.18%-78.63%33.79%-10.89%-4.14-1171.86%0.00%0.00%0.10%-5.03-6.77964.1216.11
        IMNMImmunome, Inc.$25.522.44B$14.77-42%-8.372.80256.23-5.392.8057.43%-3084.76%-3059.99%-52.09%919.14%-46.00%0.0114.6914.533.10-51.40%-23.23%22.09%-11.28%-4.24861.15%0.00%0.00%28.74%-5.27-5.63162.6320.41
        JANXJanux Therapeutics, Inc.$16.00975.75M$11.18-30%-7.410.8884.150.92-17.240.8879.71%-1576.67%-1136.25%-11.48%-954.78%-10.98%0.0239.0438.920.2742.97%-5.55%88.53%-9.90%-3.29-504.30%0.00%0.00%0.04%0.651.24-10.2910.10
        MAZEMaze Therapeutics, Inc.$27.811.54B$7.24-74%-16.466.08-14.296.080.00%0.00%0.00%-47.52%-453.11%-41.12%0.0715.5015.161.29-4020.31%-100.00%-250.70%-5.22%-4.96-357.46%0.00%0.00%0.00%-12.87-16.3128.78
        VERAVera Therapeutics, Inc.$30.352.18B-8.574.25-6.62-12.334.250.00%0.00%0.00%-50.71%1508.68%-43.10%0.13-41.8913.6413.430.9569.45%78.20%-9.42%-4.511156.04%0.00%0.00%9.33%-6.12-7.9810.06
        XERSXeris Biopharma Holdings,…$8.111.4B$29.58+265%1581.0963.993.0063.15-9.0181.70%8.53%0.19%-6.96%45.01%0.16%2.760.862.191.48-5.77-100.86%43.72%-173.79%3.19%0.2650.50%0.00%0.00%32.42%32.2428.742.750.35
        ZYMEZymeworks Inc.$23.501.73B$116.79+397%-21.256.4216.27-22.04-0.13100.00%-87.33%-76.56%-26.72%-97.68%-20.04%0.075.525.520.33-33.33%38.87%-69.48%-2.00%-0.78-36.45%0.00%0.00%2.42%-16.35-43.8314.289.49

        Disclaimer: Information on this page is provided for educational purposes only and does not constitute investment advice. Upside computed as (— ÷ $7.18) − 1 = — (IC, example).