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US · MAZE

Maze Therapeutics, Inc.

Programmatic access: InvestorsCraft Valuation API · catalog

Sector
Healthcare · Biotechnology
Headquarters
South San Francisco, CA 94080
Website
mazetx.com

Price · as of 2026-09-03

$25.87

Market cap 1.54B

Price history

Weekly OHLC price history for MAZE, USD per share
WeekOpenHighLowCloseVolume
Jan 27, 2025 – Jan 31, 2025$16.12$17.00$15.25$15.95
Feb 3, 2025 – Feb 7, 2025$15.90$16.09$11.34$13.380
Feb 10, 2025 – Feb 14, 2025$13.12$14.18$10.92$12.000
Feb 17, 2025 – Feb 21, 2025$11.75$13.42$10.80$12.090
Feb 24, 2025 – Feb 28, 2025$12.09$13.24$10.08$12.230
Mar 3, 2025 – Mar 7, 2025$12.17$13.04$10.61$12.000
Mar 10, 2025 – Mar 14, 2025$11.93$12.88$10.54$10.990
Mar 17, 2025 – Mar 21, 2025$10.85$13.00$9.88$11.140
Mar 24, 2025 – Mar 28, 2025$11.03$12.37$10.41$11.420
Mar 31, 2025 – Apr 4, 2025$10.91$11.94$8.33$9.070
Apr 7, 2025 – Apr 11, 2025$9.09$9.43$6.71$7.830
Apr 14, 2025 – Apr 17, 2025$8.10$9.13$7.52$8.410
Apr 21, 2025 – Apr 25, 2025$8.38$10.73$7.16$8.210
Apr 28, 2025 – May 2, 2025$8.25$11.98$7.79$10.850
May 5, 2025 – May 9, 2025$10.50$10.74$8.77$9.620
May 12, 2025 – May 16, 2025$10.04$10.39$8.24$9.250
May 19, 2025 – May 23, 2025$9.24$10.63$9.15$10.280
May 26, 2025 – May 30, 2025$10.58$12.25$9.73$10.010
Jun 2, 2025 – Jun 6, 2025$10.08$14.40$10.08$12.930
Jun 9, 2025 – Jun 13, 2025$13.23$13.86$12.27$13.400
Jun 16, 2025 – Jun 20, 2025$13.58$13.84$10.49$11.180
Jun 23, 2025 – Jun 27, 2025$11.13$12.93$9.83$12.130
Jun 30, 2025 – Jul 3, 2025$12.23$13.47$10.98$11.500
Jul 7, 2025 – Jul 11, 2025$11.53$15.84$11.34$15.050
Jul 14, 2025 – Jul 18, 2025$14.83$18.50$14.35$17.780
Jul 21, 2025 – Jul 25, 2025$18.26$19.19$15.17$16.820
Jul 28, 2025 – Aug 1, 2025$17.07$17.38$13.82$14.900
Aug 4, 2025 – Aug 8, 2025$14.93$15.85$12.90$13.140
Aug 11, 2025 – Aug 15, 2025$13.07$14.56$12.86$13.500
Aug 18, 2025 – Aug 22, 2025$13.49$14.02$12.81$13.490
Aug 25, 2025 – Aug 29, 2025$13.47$14.85$12.91$14.490
Sep 1, 2025 – Sep 5, 2025$14.64$16.40$14.16$15.880
Sep 8, 2025 – Sep 12, 2025$16.05$25.50$14.75$23.300
Sep 15, 2025 – Sep 19, 2025$23.33$25.18$22.04$22.940
Sep 22, 2025 – Sep 26, 2025$22.86$28.37$22.45$27.000
Sep 29, 2025 – Oct 3, 2025$27.05$27.83$24.42$27.110
Oct 6, 2025 – Oct 10, 2025$27.79$29.66$26.43$27.430
Oct 13, 2025 – Oct 17, 2025$27.43$29.76$27.41$27.810
Oct 20, 2025 – Oct 24, 2025$27.79$31.93$27.79$30.390
Oct 27, 2025 – Oct 31, 2025$30.87$34.29$30.32$32.910
Nov 3, 2025 – Nov 7, 2025$32.36$33.74$26.96$28.600
Nov 10, 2025 – Nov 14, 2025$28.17$33.76$28.17$32.530
Nov 17, 2025 – Nov 21, 2025$32.52$37.23$31.47$36.260
Nov 24, 2025 – Nov 28, 2025$36.99$38.85$35.93$37.750
Dec 1, 2025 – Dec 5, 2025$37.66$43.29$36.84$41.710
Dec 8, 2025 – Dec 12, 2025$42.14$42.50$38.10$38.860
Dec 15, 2025 – Dec 19, 2025$39.44$42.59$38.28$41.710
Dec 22, 2025 – Dec 26, 2025$41.71$43.17$41.12$42.100
Dec 29, 2025 – Jan 2, 2026$41.51$41.83$38.13$39.770
Jan 5, 2026 – Jan 9, 2026$39.77$40.99$37.37$40.320
Jan 12, 2026 – Jan 16, 2026$40.17$41.79$38.00$40.770
Jan 19, 2026 – Jan 23, 2026$40.13$47.36$38.62$44.270
Jan 26, 2026 – Jan 30, 2026$44.20$46.99$42.22$43.580
Feb 2, 2026 – Feb 6, 2026$43.56$49.25$42.17$45.030
Feb 9, 2026 – Feb 13, 2026$45.09$48.76$43.89$46.010
Feb 16, 2026 – Feb 20, 2026$46.01$48.03$42.56$44.220
Feb 23, 2026 – Feb 27, 2026$44.83$47.49$44.20$45.590
Mar 2, 2026 – Mar 6, 2026$44.50$46.65$43.00$44.830
Mar 9, 2026 – Mar 13, 2026$44.00$52.86$42.88$50.210
Mar 16, 2026 – Mar 20, 2026$50.96$53.65$46.67$48.030
Mar 23, 2026 – Mar 27, 2026$48.87$49.25$29.16$30.380
Mar 30, 2026 – Apr 2, 2026$30.37$31.23$28.00$28.710
Apr 6, 2026 – Apr 10, 2026$28.74$29.61$26.16$26.690
Apr 13, 2026 – Apr 17, 2026$27.10$29.06$26.45$28.090
Apr 20, 2026 – Apr 24, 2026$28.05$29.09$25.10$25.810
Apr 27, 2026 – May 1, 2026$25.72$27.58$25.08$27.170
May 4, 2026 – May 8, 2026$26.81$28.18$24.80$26.030
May 11, 2026 – May 15, 2026$26.22$27.13$25.02$25.560
May 18, 2026 – May 22, 2026$25.54$26.09$23.76$25.780
May 25, 2026 – May 29, 2026$25.78$26.79$25.00$26.460
Jun 1, 2026 – Jun 5, 2026$26.32$26.54$23.62$24.270
Jun 8, 2026 – Jun 12, 2026$24.76$25.08$22.71$24.050
Jun 15, 2026 – Jun 18, 2026$24.33$25.84$23.50$25.680
Jun 22, 2026 – Jun 26, 2026$25.69$29.95$25.24$28.430
Jun 29, 2026 – Jul 2, 2026$28.02$31.32$27.80$31.260
Jul 6, 2026 – Jul 10, 2026$31.25$33.50$28.99$30.570
Jul 13, 2026 – Jul 17, 2026$30.04$30.56$26.37$28.120
Jul 20, 2026 – Jul 24, 2026$28.11$29.54$27.39$27.680
Jul 27, 2026 – Jul 31, 2026$27.69$29.35$25.85$26.920
Aug 3, 2026 – Aug 7, 2026$26.74$29.00$25.85$28.650
Aug 10, 2026 – Aug 14, 2026$28.57$28.92$26.42$27.180
Aug 17, 2026 – Aug 21, 2026$27.04$30.19$27.00$29.430
Aug 24, 2026 – Aug 28, 2026$29.27$30.80$27.31$27.440
Aug 31, 2026 – Sep 3, 2026$27.17$27.44$25.70$25.870

Valuation

MetricValueUpside
IC Value$7.24-72%
P/E-16.46
P/B6.08
P/S
EV/EBITDA-14.29
PEG
P/TBV6.08

Valuation history

Annual price overlaid with each model's fair value. Y-axis is log scale.

Annual price and model valuations for MAZE, USD per share
YearPriceAIICGraham-DoddGraham Formula
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024$12.00
2025$50.21

Historic valuation ratios

Pick a category, then toggle metrics to compare.

USD millions

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        About Maze Therapeutics, Inc.

        Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor that is in phase II ready clinical trial for the treatment of phenylketonuria and chronic kidney disease. The company also develops MZE001, an investigational oral small molecule inhibitor of muscle-specific glycogen synthase clinical program for the treatment of Pompe disease. It has a license agreement with Trace Neuroscience, Inc. to discovery research program targets UNC13A; the Shionogi & Co., Ltd to research, develop, manufacture, and commercialize MZE001; and Neurocrine Biosciences, Inc. to discover research program that targets ATXN2. The company was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.

        CEO
        Jason Coloma
        Employees
        141
        Beta
        2.14

        Peer comparison

        Same-industry comparables, ranked by market cap.

        Scroll horizontally for additional metrics. Ticker column stays fixed.

        Peer comparison for MAZE: basic info, valuation models, ratios, profitability, leverage, growth, cash flow, dividends, enterprise value, and Altman Z-score.
        Basic InfoIC ValuationCore ValuationProfitabilityLeverage & LiquidityGrowthCash FlowDividendsEnterprise ValueRisk
        TickerCompany NamePriceMarket CapValueUpsideP/EP/BP/SEV/EBITDAPEGP/TBVGross MarginOperating MarginNet MarginROEROICROADebt/EquityInterest CoverageCurrent RatioQuick RatioNet Debt/EBITDAEPS GrowthSales GrowthFCF GrowthFCF YieldOp Cash Flow RatioCash ROICDividend YieldDividend PayoutShareholder YieldEV/EBITEV/FCFEV/SalesAltman Z-Score
        MAZEMaze Therapeutics, Inc.$28.651.54B$7.24-75%-16.466.08-14.296.080.00%0.00%0.00%-47.52%-453.11%-41.12%0.0715.5015.161.29-4020.31%-100.00%-250.70%-5.22%-4.96-357.46%0.00%0.00%0.00%-12.87-16.3128.78
        ARDXArdelyx, Inc.$4.911.21B$15.11+208%-22.628.343.42-45.94-42.728.3489.54%-10.06%-15.12%-36.21%-43.02%-13.14%1.27-1.444.313.80-4.9252.94%22.09%-4.03%-3.16%-0.48-46.17%0.00%0.00%0.00%-32.70-30.473.291.10
        BCRXBioCryst Pharmaceuticals,…$9.072.31B$71.19+685%6.54-14.481.975.43-14.4897.82%38.98%30.16%-88.68%752.79%52.53%-3.684.322.061.951.00-381.40%94.10%-716.08%18.98%1.68732.48%0.00%0.00%22.45%5.545.772.161.91
        IMNMImmunome, Inc.$25.522.44B$14.77-42%-8.372.80256.23-5.392.8057.43%-3084.76%-3059.99%-52.09%919.14%-46.00%0.0114.6914.533.10-51.40%-23.23%22.09%-11.28%-4.24861.15%0.00%0.00%28.74%-5.27-5.63162.6320.41
        NTLAIntellia Therapeutics, In…$10.971.23B$9.46-14%-2.662.0620.44-2.592.0676.47%-651.67%-609.85%-67.26%-110.87%-51.06%0.145.084.420.16-27.43%16.92%0.00%-25.65%-3.36-89.17%0.00%0.00%6.01%-2.33-2.8915.17-0.49
        PHVSPharvaris N.V.$33.422.34B-7.494.79-5.83-37.904.790.00%0.00%0.00%-64.45%1070.30%-58.60%0.0010.1110.011.6819.76%13.73%-10.55%-4.63864.94%0.00%0.00%0.85%-5.95-7.3622.38
        SIONSionna Therapeutics, Inc.$47.342.14B-19.814.86-16.94-57.794.860.00%0.00%0.00%-105.18%80.21%-29.42%0.0320.6120.140.6734.29%26.24%-4.47%-5.6660.10%0.00%0.00%1.46%-14.21-18.9645.64
        SYRESpyre Therapeutics, Inc.$104.359.06B-16.463.57-8.583.570.00%0.00%0.00%-25.17%331.08%-22.39%0.0013.2512.890.41-37.74%7.52%-6.62%-2.88267.42%0.00%0.00%0.00%-8.58-10.6322.70
        TRVITrevi Therapeutics, Inc.$18.652.65B-37.368.72-33.048.720.00%0.00%0.00%-30.23%878.83%-28.10%0.0019.6619.410.43-38.30%9.95%-2.64%-4.32751.20%0.00%0.00%0.00%-28.59-33.4991.92
        WVEWave Life Sciences Ltd.$5.931.17B$15.97+169%-10.744.1751.39-8.24-14.754.1779.28%-504.09%-478.33%-55.56%343.98%-41.26%0.036.476.352.9972.86%-60.55%23.85%-8.57%-1.97300.58%0.00%0.00%14.01%-7.48-8.5637.728.76
        ZYMEZymeworks Inc.$23.501.73B$116.79+397%-21.256.4216.27-22.04-0.13100.00%-87.33%-76.56%-26.72%-97.68%-20.04%0.075.525.520.33-33.33%38.87%-69.48%-2.00%-0.78-36.45%0.00%0.00%2.42%-16.35-43.8314.289.49

        Disclaimer: Information on this page is provided for educational purposes only and does not constitute investment advice. Upside computed as ($7.24 ÷ $25.87) − 1 = -72.01% (IC, example).