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US · GPCR

Structure Therapeutics Inc.

Programmatic access: InvestorsCraft Valuation API · catalog

Sector
Healthcare · Biotechnology
Headquarters
South San Francisco, CA 94080

Price · as of 2026-09-04

$47.34

Market cap 2.91B

Price history

Weekly OHLC price history for GPCR, USD per share
WeekOpenHighLowCloseVolume
Jan 30, 2023 – Feb 3, 2023$25.00$27.46$23.00$26.00
Feb 6, 2023 – Feb 10, 2023$24.34$27.00$22.29$23.000
Feb 13, 2023 – Feb 17, 2023$22.96$26.51$21.25$22.140
Feb 20, 2023 – Feb 24, 2023$22.00$26.56$20.80$24.300
Feb 27, 2023 – Mar 3, 2023$24.44$30.00$22.50$26.550
Mar 6, 2023 – Mar 10, 2023$27.40$27.73$23.00$23.540
Mar 13, 2023 – Mar 17, 2023$23.20$25.34$21.12$23.120
Mar 20, 2023 – Mar 24, 2023$22.35$24.49$22.15$22.750
Mar 27, 2023 – Mar 31, 2023$22.79$25.50$21.21$23.790
Apr 3, 2023 – Apr 6, 2023$23.27$27.48$22.74$24.500
Apr 10, 2023 – Apr 14, 2023$24.20$25.09$22.81$24.280
Apr 17, 2023 – Apr 21, 2023$24.02$25.00$23.31$25.000
Apr 24, 2023 – Apr 28, 2023$24.75$25.82$23.60$25.430
May 1, 2023 – May 5, 2023$25.48$25.48$23.00$23.650
May 8, 2023 – May 12, 2023$23.50$27.50$22.95$26.400
May 15, 2023 – May 19, 2023$26.14$28.81$21.79$24.240
May 22, 2023 – May 26, 2023$23.81$36.00$23.73$32.000
May 29, 2023 – Jun 2, 2023$29.97$33.27$29.97$31.930
Jun 5, 2023 – Jun 9, 2023$32.27$35.00$31.13$34.010
Jun 12, 2023 – Jun 16, 2023$34.01$34.34$29.58$31.980
Jun 19, 2023 – Jun 23, 2023$31.85$32.84$28.62$29.320
Jun 26, 2023 – Jun 30, 2023$30.14$42.55$30.14$41.570
Jul 3, 2023 – Jul 7, 2023$41.73$42.52$33.72$35.040
Jul 10, 2023 – Jul 14, 2023$34.90$35.80$30.66$33.700
Jul 17, 2023 – Jul 21, 2023$34.48$36.99$32.26$34.080
Jul 24, 2023 – Jul 28, 2023$34.08$36.92$33.65$36.220
Jul 31, 2023 – Aug 4, 2023$36.28$37.67$27.77$29.250
Aug 7, 2023 – Aug 11, 2023$28.94$32.50$25.86$27.570
Aug 14, 2023 – Aug 18, 2023$27.42$28.35$25.57$27.880
Aug 21, 2023 – Aug 25, 2023$27.35$30.09$27.29$29.670
Aug 28, 2023 – Sep 1, 2023$30.10$31.40$27.52$29.370
Sep 4, 2023 – Sep 8, 2023$29.36$29.60$27.23$28.070
Sep 11, 2023 – Sep 15, 2023$28.11$32.96$27.65$32.650
Sep 18, 2023 – Sep 22, 2023$31.35$36.25$31.19$34.000
Sep 25, 2023 – Sep 29, 2023$33.82$65.51$32.18$50.420
Oct 2, 2023 – Oct 6, 2023$50.83$60.72$50.37$55.120
Oct 9, 2023 – Oct 13, 2023$54.75$67.83$54.50$65.050
Oct 16, 2023 – Oct 20, 2023$65.15$69.10$63.21$67.520
Oct 23, 2023 – Oct 27, 2023$66.02$70.70$64.28$68.170
Oct 30, 2023 – Nov 3, 2023$69.65$75.02$67.31$69.880
Nov 6, 2023 – Nov 10, 2023$69.88$72.16$52.36$54.870
Nov 13, 2023 – Nov 17, 2023$54.00$56.38$42.25$53.770
Nov 20, 2023 – Nov 24, 2023$54.67$56.01$50.44$51.520
Nov 27, 2023 – Dec 1, 2023$52.00$60.05$49.78$59.570
Dec 4, 2023 – Dec 8, 2023$59.78$66.38$58.94$61.870
Dec 11, 2023 – Dec 15, 2023$62.13$62.20$54.17$59.160
Dec 18, 2023 – Dec 22, 2023$31.90$40.30$26.61$35.590
Dec 25, 2023 – Dec 29, 2023$35.36$40.78$35.22$40.760
Jan 1, 2024 – Jan 5, 2024$39.60$42.93$38.66$42.360
Jan 8, 2024 – Jan 12, 2024$42.36$50.73$41.06$45.800
Jan 15, 2024 – Jan 19, 2024$45.63$46.59$40.69$40.770
Jan 22, 2024 – Jan 26, 2024$40.77$42.74$39.76$42.500
Jan 29, 2024 – Feb 2, 2024$42.42$45.88$41.01$43.780
Feb 5, 2024 – Feb 9, 2024$43.70$49.55$42.98$49.000
Feb 12, 2024 – Feb 16, 2024$49.87$50.07$44.00$45.800
Feb 19, 2024 – Feb 23, 2024$45.75$47.38$40.31$40.510
Feb 26, 2024 – Mar 1, 2024$40.89$44.95$39.88$41.240
Mar 4, 2024 – Mar 8, 2024$42.15$43.85$35.42$36.860
Mar 11, 2024 – Mar 15, 2024$37.57$37.57$33.65$35.250
Mar 18, 2024 – Mar 22, 2024$35.72$45.74$34.20$42.880
Mar 25, 2024 – Mar 28, 2024$42.70$44.85$40.66$42.860
Apr 1, 2024 – Apr 5, 2024$43.26$43.77$38.67$41.460
Apr 8, 2024 – Apr 12, 2024$42.26$45.11$38.94$39.320
Apr 15, 2024 – Apr 19, 2024$39.50$39.88$35.70$36.360
Apr 22, 2024 – Apr 26, 2024$36.49$39.47$35.53$38.940
Apr 29, 2024 – May 3, 2024$39.24$41.13$37.85$39.290
May 6, 2024 – May 10, 2024$39.45$41.66$35.77$35.820
May 13, 2024 – May 17, 2024$36.35$38.15$35.29$36.150
May 20, 2024 – May 24, 2024$36.16$40.00$35.08$37.060
May 27, 2024 – May 31, 2024$37.32$38.30$33.74$34.200
Jun 3, 2024 – Jun 7, 2024$35.45$62.74$33.56$53.070
Jun 10, 2024 – Jun 14, 2024$53.00$54.08$46.60$48.170
Jun 17, 2024 – Jun 21, 2024$48.39$49.91$44.64$45.570
Jun 24, 2024 – Jun 28, 2024$45.14$45.68$36.45$39.270
Jul 1, 2024 – Jul 5, 2024$40.01$41.21$37.15$37.770
Jul 8, 2024 – Jul 12, 2024$38.32$46.05$36.75$43.880
Jul 15, 2024 – Jul 19, 2024$43.95$47.48$36.01$37.440
Jul 22, 2024 – Jul 26, 2024$37.58$39.50$34.87$38.650
Jul 29, 2024 – Aug 2, 2024$38.87$40.26$34.98$35.880
Aug 5, 2024 – Aug 9, 2024$33.97$37.29$32.57$33.770
Aug 12, 2024 – Aug 16, 2024$34.12$37.78$32.85$37.120
Aug 19, 2024 – Aug 23, 2024$37.23$41.41$37.12$39.790
Aug 26, 2024 – Aug 30, 2024$39.77$41.48$37.60$38.130
Sep 2, 2024 – Sep 6, 2024$37.43$39.30$36.30$36.950
Sep 9, 2024 – Sep 13, 2024$37.13$42.67$33.95$40.840
Sep 16, 2024 – Sep 20, 2024$40.63$42.62$36.72$41.920
Sep 23, 2024 – Sep 27, 2024$45.00$45.37$40.62$41.750
Sep 30, 2024 – Oct 4, 2024$42.39$44.72$41.33$42.990
Oct 7, 2024 – Oct 11, 2024$43.46$43.46$37.71$38.320
Oct 14, 2024 – Oct 18, 2024$38.21$40.34$34.83$39.500
Oct 21, 2024 – Oct 25, 2024$39.40$39.82$37.19$37.590
Oct 28, 2024 – Nov 1, 2024$37.84$42.57$36.56$41.140
Nov 4, 2024 – Nov 8, 2024$40.84$42.22$37.41$38.020
Nov 11, 2024 – Nov 15, 2024$38.74$40.06$33.85$34.170
Nov 18, 2024 – Nov 22, 2024$33.91$34.00$29.48$33.410
Nov 25, 2024 – Nov 29, 2024$33.67$35.31$32.83$33.150
Dec 2, 2024 – Dec 6, 2024$32.97$35.60$30.45$33.350
Dec 9, 2024 – Dec 13, 2024$35.50$36.42$30.81$31.250
Dec 16, 2024 – Dec 20, 2024$31.01$32.00$26.23$27.900
Dec 23, 2024 – Dec 27, 2024$28.53$30.44$27.78$29.040
Dec 30, 2024 – Jan 3, 2025$28.59$28.87$25.90$27.760
Jan 6, 2025 – Jan 10, 2025$28.00$28.39$24.95$25.260
Jan 13, 2025 – Jan 17, 2025$25.16$27.68$23.50$27.060
Jan 20, 2025 – Jan 24, 2025$27.34$29.00$26.87$28.220
Jan 27, 2025 – Jan 31, 2025$27.64$31.72$27.64$29.970
Feb 3, 2025 – Feb 7, 2025$28.82$31.33$27.28$27.400
Feb 10, 2025 – Feb 14, 2025$27.45$27.45$23.65$24.390
Feb 17, 2025 – Feb 21, 2025$23.99$24.87$22.33$23.770
Feb 24, 2025 – Feb 28, 2025$23.51$24.13$19.61$23.750
Mar 3, 2025 – Mar 7, 2025$23.77$23.77$20.45$22.620
Mar 10, 2025 – Mar 14, 2025$22.11$23.00$19.39$21.050
Mar 17, 2025 – Mar 21, 2025$21.00$23.48$20.85$20.970
Mar 24, 2025 – Mar 28, 2025$21.10$21.71$18.87$19.770
Mar 31, 2025 – Apr 4, 2025$19.22$19.22$14.88$15.120
Apr 7, 2025 – Apr 11, 2025$14.46$16.06$13.22$15.900
Apr 14, 2025 – Apr 17, 2025$18.00$24.17$16.80$21.760
Apr 21, 2025 – Apr 25, 2025$21.57$24.45$21.01$23.740
Apr 28, 2025 – May 2, 2025$23.74$28.68$23.61$27.090
May 5, 2025 – May 9, 2025$26.91$27.78$25.06$25.570
May 12, 2025 – May 16, 2025$26.38$26.90$21.85$25.170
May 19, 2025 – May 23, 2025$25.08$25.80$23.81$24.550
May 26, 2025 – May 30, 2025$24.83$24.98$21.51$21.760
Jun 2, 2025 – Jun 6, 2025$21.97$22.98$21.00$21.130
Jun 9, 2025 – Jun 13, 2025$21.56$24.05$20.27$21.680
Jun 16, 2025 – Jun 20, 2025$21.57$22.33$20.42$21.730
Jun 23, 2025 – Jun 27, 2025$21.91$23.67$20.70$21.080
Jun 30, 2025 – Jul 3, 2025$21.14$21.40$19.83$20.360
Jul 7, 2025 – Jul 11, 2025$20.40$20.61$18.50$19.010
Jul 14, 2025 – Jul 18, 2025$18.88$20.25$18.75$19.250
Jul 21, 2025 – Jul 25, 2025$19.20$19.59$17.45$17.940
Jul 28, 2025 – Aug 1, 2025$18.13$18.78$17.50$17.590
Aug 4, 2025 – Aug 8, 2025$17.50$17.81$15.80$16.310
Aug 11, 2025 – Aug 15, 2025$16.37$20.36$16.00$20.120
Aug 18, 2025 – Aug 22, 2025$20.21$21.44$18.39$19.610
Aug 25, 2025 – Aug 29, 2025$19.72$19.73$18.26$19.300
Sep 1, 2025 – Sep 5, 2025$19.20$22.25$18.49$22.080
Sep 8, 2025 – Sep 12, 2025$22.03$22.08$20.29$20.910
Sep 15, 2025 – Sep 19, 2025$20.91$23.75$20.04$23.580
Sep 22, 2025 – Sep 26, 2025$24.86$26.15$23.59$25.000
Sep 29, 2025 – Oct 3, 2025$25.04$28.12$24.63$27.280
Oct 6, 2025 – Oct 10, 2025$27.45$30.93$27.45$30.070
Oct 13, 2025 – Oct 17, 2025$30.15$31.08$27.00$27.380
Oct 20, 2025 – Oct 24, 2025$27.87$28.26$25.59$26.390
Oct 27, 2025 – Oct 31, 2025$26.74$34.10$26.62$33.320
Nov 3, 2025 – Nov 7, 2025$33.10$34.50$30.95$32.840
Nov 10, 2025 – Nov 14, 2025$33.72$37.60$33.00$36.820
Nov 17, 2025 – Nov 21, 2025$36.77$40.29$33.81$34.320
Nov 24, 2025 – Nov 28, 2025$34.06$35.86$33.36$35.810
Dec 1, 2025 – Dec 5, 2025$35.26$36.09$30.94$34.560
Dec 8, 2025 – Dec 12, 2025$45.33$94.90$44.74$67.060
Dec 15, 2025 – Dec 19, 2025$67.08$69.30$58.84$64.940
Dec 22, 2025 – Dec 26, 2025$64.91$72.00$61.87$68.340
Dec 29, 2025 – Jan 2, 2026$68.00$70.40$65.60$68.120
Jan 5, 2026 – Jan 9, 2026$68.15$69.78$61.99$68.610
Jan 12, 2026 – Jan 16, 2026$68.93$92.85$68.50$88.640
Jan 19, 2026 – Jan 23, 2026$88.36$94.77$86.75$90.370
Jan 26, 2026 – Jan 30, 2026$89.60$91.21$86.10$88.450
Feb 2, 2026 – Feb 6, 2026$87.58$92.06$72.10$74.920
Feb 9, 2026 – Feb 13, 2026$75.20$81.15$69.95$70.070
Feb 16, 2026 – Feb 20, 2026$69.61$72.31$64.96$66.550
Feb 23, 2026 – Feb 27, 2026$67.78$69.00$62.17$62.980
Mar 2, 2026 – Mar 6, 2026$61.88$64.99$57.02$57.730
Mar 9, 2026 – Mar 13, 2026$56.85$60.61$52.51$53.750
Mar 16, 2026 – Mar 20, 2026$56.58$61.20$47.71$48.590
Mar 23, 2026 – Mar 27, 2026$49.42$51.39$44.77$45.920
Mar 30, 2026 – Apr 2, 2026$45.66$55.75$42.72$53.480
Apr 6, 2026 – Apr 10, 2026$53.48$57.23$50.23$54.510
Apr 13, 2026 – Apr 17, 2026$53.50$56.40$50.55$50.750
Apr 20, 2026 – Apr 24, 2026$50.05$50.70$45.06$45.490
Apr 27, 2026 – May 1, 2026$45.79$47.49$40.68$42.210
May 4, 2026 – May 8, 2026$42.15$44.78$37.69$39.100
May 11, 2026 – May 15, 2026$39.01$40.14$36.92$38.690
May 18, 2026 – May 22, 2026$38.63$40.38$35.78$39.190
May 25, 2026 – May 29, 2026$39.19$41.50$38.05$39.340
Jun 1, 2026 – Jun 5, 2026$39.34$39.82$36.53$37.580
Jun 8, 2026 – Jun 12, 2026$37.47$43.50$36.45$42.930
Jun 15, 2026 – Jun 18, 2026$43.00$47.24$41.71$44.510
Jun 22, 2026 – Jun 26, 2026$44.51$50.29$43.99$49.710
Jun 29, 2026 – Jul 2, 2026$49.71$55.00$49.11$53.450
Jul 6, 2026 – Jul 10, 2026$53.20$57.07$52.45$53.360
Jul 13, 2026 – Jul 17, 2026$52.75$53.00$44.80$48.480
Jul 20, 2026 – Jul 24, 2026$48.48$52.60$46.06$49.120
Jul 27, 2026 – Jul 31, 2026$49.35$51.30$46.40$48.040
Aug 3, 2026 – Aug 7, 2026$48.04$54.80$46.58$53.140
Aug 10, 2026 – Aug 14, 2026$53.19$55.00$51.00$54.510
Aug 17, 2026 – Aug 21, 2026$54.00$55.60$49.01$49.090
Aug 24, 2026 – Aug 28, 2026$48.61$51.02$46.96$47.370
Aug 31, 2026 – Sep 4, 2026$47.08$48.64$45.10$47.340

Valuation

MetricValueUpside
IC Value
P/E-22.53
P/B2.10
P/S
EV/EBITDA-12.74
PEG-878.85
P/TBV2.10

Valuation history

Annual price overlaid with each model's fair value. Y-axis is log scale.

Annual price and model valuations for GPCR, USD per share
YearPriceAIICGraham-DoddGraham Formula
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022$23.54
2023$36.86
2024$22.62
2025$53.75

Historic valuation ratios

Pick a category, then toggle metrics to compare.

USD millions

Line items

    USD millions

    Line items

      USD millions

      Line items

        About Structure Therapeutics Inc.

        Structure Therapeutics Inc., an international biopharmaceutical company currently in its clinical development phase, is committed to creating and providing groundbreaking oral therapies for various chronic diseases that lack adequate treatment options. The company's primary investigational drug, GSBR-1290, is an orally administered, biased small molecule agonist designed to target the glucagon-like-peptide-1 receptor (GLP-1R). This G-protein-coupled receptor (GPCR) is a recognized and validated therapeutic target for managing both type-2 diabetes mellitus and obesity. Furthermore, Structure Therapeutics is developing other oral small molecule treatments that act on different GPCRs, addressing pulmonary and cardiovascular conditions. For example, ANPA-0073 is a biased agonist aimed at the apelin receptor, a GPCR linked to diseases like idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension. Another compound in their pipeline is LTSE-2578, an oral small molecule that acts as a lysophosphatidic acid 1 receptor antagonist, also being explored for the treatment of IPF. Established in 2016, the company was formerly known as ShouTi Inc. and is headquartered in South San Francisco, California.

        CEO
        Raymond C. Stevens
        Employees
        220
        Beta
        -1.57

        Peer comparison

        Same-industry comparables, ranked by market cap.

        Scroll horizontally for additional metrics. Ticker column stays fixed.

        Peer comparison for GPCR: basic info, valuation models, ratios, profitability, leverage, growth, cash flow, dividends, enterprise value, and Altman Z-score.
        Basic InfoIC ValuationCore ValuationProfitabilityLeverage & LiquidityGrowthCash FlowDividendsEnterprise ValueRisk
        TickerCompany NamePriceMarket CapValueUpsideP/EP/BP/SEV/EBITDAPEGP/TBVGross MarginOperating MarginNet MarginROEROICROADebt/EquityInterest CoverageCurrent RatioQuick RatioNet Debt/EBITDAEPS GrowthSales GrowthFCF GrowthFCF YieldOp Cash Flow RatioCash ROICDividend YieldDividend PayoutShareholder YieldEV/EBITEV/FCFEV/SalesAltman Z-Score
        GPCRStructure Therapeutics In…$53.142.91B-22.532.10-12.74-878.852.100.00%0.00%0.00%-11.86%-929.83%-11.35%0.0024.8122.855.802.56%91.49%-7.10%-3.51-730.15%0.00%0.00%19.72%-6.06-7.7228.39
        ABCLAbCellera Biologics Inc.$5.921.81B$20.45+245%-7.121.0813.88-4.381.1861.64%-288.98%-194.88%-14.47%-33.39%-10.78%0.1511.3210.69-0.10-10.91%160.56%-6.89%-16.70%-2.04-32.47%0.00%0.00%0.00%-3.00-3.748.681.69
        CLDXCelldex Therapeutics, Inc…$41.062.73B$15.31-63%-7.583.721308.28-5.66-12.813.93100.00%-19160.00%-17253.33%-40.62%-1576.31%-37.63%0.0010.4910.210.1059.18%-78.63%33.79%-10.89%-4.14-1171.86%0.00%0.00%0.10%-5.03-6.77964.1216.11
        EWTXEdgewise Therapeutics, In…$44.994.84B-18.155.83-15.22-146.225.830.00%0.00%0.00%-34.19%3798.11%-32.29%0.0119.8519.370.3512.41%30.57%-4.73%-5.252858.86%0.00%0.00%0.66%-13.16-17.4958.81
        LQDALiquidia Corporation$89.127.93B$81.57-8%-45.7770.5019.93-73.1683.2691.64%-32.45%-43.53%-112.97%-136.67%-24.69%4.42-2.131.401.80-0.17-51.81%1031.18%-59.32%-1.27%-0.26-106.47%0.00%0.00%0.00%-61.55-79.0119.974.18
        MESOMesoblast Limited$14.961.94B$24.02+61%-17.022.91101.06-23.1567.8570.17%-363.08%-593.92%-18.95%-11.34%-14.05%0.21-2.721.991.720.45-5.62%191.39%3.88%-2.92%-0.49-9.21%0.00%0.00%5.14%-27.31-33.6499.143.68
        NUVBNuvation Bio Inc.$6.372.21B$48.97+669%-7.414.9624.11-5.275.1586.58%-338.72%-325.31%-53.18%175.12%-36.04%0.03-15.576.956.670.81-71.56%698.96%33.09%-11.46%-2.11142.83%0.00%0.00%8.38%-4.68-5.7415.860.43
        OCULOcular Therapeutix, Inc.$8.501.86B$13.59+60%-6.172.5131.65-3.94-37.622.5187.31%-521.04%-513.17%-54.85%13699.49%-42.01%0.12-22.8215.3915.112.6316.39%-18.67%59.52%-13.22%-4.0311004.21%0.00%0.00%20.79%-3.64-4.5318.974.44
        QUREuniQure N.V.$44.243.07B$13.15-70%-4.494.4955.47-6.928.8689.53%-1166.77%-1236.00%-207.10%192.39%-28.81%2.70-3.0310.439.99-3.91-29.67%-40.64%-4.13%-19.98%-2.83182.73%0.00%0.00%0.00%-4.30-4.5250.13-1.27
        VRDNViridian Therapeutics, In…$21.071.9B$1,773.22+8,316%-7.103.3734.33-4.773.37100.00%-512.91%-483.57%-49.16%573.89%-41.73%0.07-73.4412.6512.370.48-16.58%23359.93%18.92%-11.38%-3.91437.27%0.00%0.00%3.42%-4.43-5.8122.705.99

        Disclaimer: Information on this page is provided for educational purposes only and does not constitute investment advice. Upside computed as (— ÷ $47.34) − 1 = — (IC, example).